TB-500 Certificates of Analysis

Information for TB-500

TB-500 is a synthetic peptide derivative of thymosin β4 (Tβ4) whose biological activity remains unconfirmed; current research has instead focused on its metabolic degradation and analytical profiling (Rahaman et al. 2024). Among the identified metabolites, only Ac-LKKTE exhibited in vitro wound healing activity, indicating that previous functional effects attributed to TB-500 may be due to this specific metabolite (Rahaman et al. 2024).

References

Morris, D. C., Chopp, M., Zhang, L., Lu, M., & Zhang, Z. G. (2010). Thymosin β4 improves functional neurological outcome in a rat model of embolic stroke. Neuroscience, 169(2), 674– 682. https://doi.org/10.1016/j.neuroscience.2010.05.017

Rahaman, K. A., Muresan, A. R., Min, H., Son, J., Han, H.-S., Kang, M.-J., & Kwon, O.-S. (2024). Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in vitro. Journal of Chromatography B, 1235, 124033. https://doi.org/10.1016/j.jchromb.2024.124033

GMP Certificates of Analysis

TB-500

10.14mg

Batch V260302-16 003

3/25/2026

Research Certificates of Analysis

TB-500

5.52mg

Batch V260409-12 004

Lot #40826

4/28/2026

TB-500 Peptide Structure

Source: PubChem

PubChem Identifier: CID 16132341

Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser

Molecular Formula: C212H350N56O78S

Molecular Weight: 4963.4408 g/mol

CAS Number: 77591-33-4

Product Usage

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.